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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RBL2
All Species:
19.39
Human Site:
T431
Identified Species:
35.56
UniProt:
Q08999
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q08999
NP_005602.3
1139
128367
T431
H
S
L
S
R
L
H
T
M
L
T
G
L
R
N
Chimpanzee
Pan troglodytes
XP_523371
1139
128318
T431
H
S
L
S
R
L
H
T
M
L
T
G
L
R
N
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535303
1139
128252
T431
H
S
L
S
R
L
H
T
M
L
T
G
L
R
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64700
1135
127455
T428
H
S
L
S
R
L
H
T
M
L
S
G
L
R
N
Rat
Rattus norvegicus
O55081
1135
127799
T428
H
S
L
N
R
L
H
T
M
L
A
G
L
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520195
1071
120785
K404
Q
S
I
A
N
R
L
K
E
M
Y
E
L
Y
C
Chicken
Gallus gallus
Q90600
921
104417
I257
N
A
R
A
S
K
Q
I
D
T
D
T
K
V
I
Frog
Xenopus laevis
NP_001084880
998
113114
E334
G
R
G
Y
L
K
E
E
Q
T
V
I
T
P
V
Zebra Danio
Brachydanio rerio
XP_002667000
970
107485
E306
S
C
V
R
D
P
T
E
S
V
A
A
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24472
845
96808
H181
S
L
H
G
N
H
A
H
G
K
C
S
Y
I
K
Honey Bee
Apis mellifera
XP_395096
1006
113492
L342
Q
M
M
N
V
G
D
L
H
E
Q
F
Q
M
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
D371
R
V
F
I
N
E
E
D
S
L
L
G
S
G
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LKZ3
1013
112157
S349
V
F
I
N
E
E
D
S
L
L
G
S
G
S
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
97.1
N.A.
90.9
90
N.A.
79.8
21.8
43.2
53
N.A.
23.5
40.2
N.A.
N.A.
Protein Similarity:
100
99.9
N.A.
98.7
N.A.
94.9
94.8
N.A.
87.1
38.3
61.2
65.5
N.A.
40.6
57.5
N.A.
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
93.3
86.6
N.A.
13.3
0
0
0
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
100
93.3
N.A.
33.3
20
0
13.3
N.A.
0
13.3
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
21.8
N.A.
N.A.
Protein Similarity:
39.6
N.A.
N.A.
39.3
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
0
8
0
0
0
16
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
8
% C
% Asp:
0
0
0
0
8
0
16
8
8
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
8
16
16
16
8
8
0
8
0
0
0
% E
% Phe:
0
8
8
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
8
0
8
0
0
8
0
8
47
8
8
0
% G
% His:
39
0
8
0
0
8
39
8
8
0
0
0
0
0
0
% H
% Ile:
0
0
16
8
0
0
0
8
0
0
0
8
0
8
8
% I
% Lys:
0
0
0
0
0
16
0
8
0
8
0
0
8
0
24
% K
% Leu:
0
8
39
0
8
39
8
8
8
54
8
0
47
8
8
% L
% Met:
0
8
8
0
0
0
0
0
39
8
0
0
0
8
0
% M
% Asn:
8
0
0
24
24
0
0
0
0
0
0
0
0
0
39
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
16
0
0
0
0
0
8
0
8
0
8
0
8
0
0
% Q
% Arg:
8
8
8
8
39
8
0
0
0
0
0
0
8
39
0
% R
% Ser:
16
47
0
31
8
0
0
8
16
0
8
16
8
8
8
% S
% Thr:
0
0
0
0
0
0
8
39
0
16
24
8
8
0
0
% T
% Val:
8
8
8
0
8
0
0
0
0
8
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
8
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _